clot

Examples of clot in the following topics:

• Platelets and Coagulation Factors

  • Blood must form clots to heal wounds and prevent excess blood loss.
  • Many of the clotting factors require vitamin K to function.
  • Vitamin K deficiency can lead to problems with blood clotting.
  • The plug or clot lasts for a number of days, stopping the loss of blood.
  • (b) Platelets are required for clotting of the blood.

• Bone Remodeling and Repair

  • Hematoma formation: Blood vessels in the broken bone tear and hemorrhage, resulting in the formation of clotted blood, or a hematoma, at the site of the break.
  • The severed blood vessels at the broken ends of the bone are sealed by the clotting process.
  • Though fragments of the blood clot may remain, fibroblasts and osteoblasts enter the area and begin to reform bone.

• The Role of Blood in the Body

  • Coagulation, which is one part of the body's self-repair mechanism (blood clotting by the platelets after an open wound in order to stop bleeding)
  • Platelets form clots that prevent blood loss after injury.

• Extracellular Matrix of Animal Cells

  • An example of the role of the extracellular matrix in cell communication can be seen in blood clotting.
  • Subsequently, a series of steps are initiated which then prompt the platelets to produce clotting factors.

• Control of Homeostasis

  • There are few examples of positive feedback loops that exist in animal bodies, but one is found in the cascade of chemical reactions that result in blood clotting, or coagulation.
  • As one clotting factor is activated, it activates the next factor in sequence until a fibrin clot is achieved.

• Other Neurological Disorders

  • Stroke is often caused by blood clots, but can also be caused by the bursting of a weak blood vessel.

• Parathyroid Glands

  • Blood cannot clot without sufficient calcium.

• Biotechnology in Medicine

  • Since then, modern biotechnology has made it possible to produce more easily and cheaply the human growth hormone, clotting factors for hemophiliacs, fertility drugs, erythropoietin, and other drugs.

• Female Hormones

  • Supplementation of estrogen in the form of hormone replacement therapy (HRT) can prevent bone loss, but the therapy can have negative side effects, such as an increased risk of stroke or heart attack, blood clots, breast cancer, ovarian cancer, endometrial cancer, gall bladder disease, and, possibly, dementia.

• Human Gestation

  • Clots may form in her legs due to pressure from the fetus on returning veins as they enter the abdominal cavity.